Publications
2025
Enhancing the efficacy, utility and throughput of the Transcription Block Survival peptide library screening platform
Andrew Brennan, T. M. Simon Tang, Jody M. Mason
JACS Au: 10.1021/jacsau.5c00628
Stabilizing a Native Fold of Alpha-Synuclein with Short Helix-Constrained Peptides
Richard M. Meade, Scott G. Allen, Amy Lopez, Christopher Williams, Iona Thomas-Wright, Rachel Heon-Roberts, Mara Carey-Wood, T M Simon Tang, Julia Sero, Vicky Hunt, Richard Wade-Martins, Matthew P Crump, Jody M Mason
JACS Au: 10.1021/jacsau.5c00694
2024
Exponential Combination of a and e/g Intracellular Peptide Libraries Identifies a Selective ATF3 Inhibitor
Miao Yu, T. M. Simon Tang, Lila Ghamsari, Graham Yuen, Claudio Scuoppo, Jim A. Rotolo, Barry J. Kappel, Jody M. Mason
ACS Chemical Biology: 10.1021/acschembio.3c00779
Towards Controlling Activity of a Peptide Asparaginyl Ligase (PAL) by Lumazine Synthetase
Simon Tang, Louis Luk
Faraday Discussions: 10.1039/D4FD00002A
2023
An N-terminal alpha-Synuclein fragment binds lipid vesicles to modulate lipid induced aggregation
Richard Meade, Scott Allen, Chris Williams, T. M. Simon Tang, Matthew P Crump, Jody M. Mason
Cell Reports Physical Science: 10.1016/j.xcrp.2023.101563
Intracellular application of an asparaginyl endopeptidase for producing recombinant head-to-tail cyclic proteins
T. M. Simon Tang, Jody Mason
JACS Au: 10.1021/jacsau.3c00591
Preparing recombinant “Split AEP” for protein labeling
Muge Ma, T. M. Simon Tang, Matthew T. Dickerson, Louis Luk
Modern Methods of Drug Design and Development: 10.1016/bs.mie.2023.07.004
2021
Asparaginyl endopeptidases: enzymology, applications and limitations
T. M. Simon Tang, Louis Luk
Organic & Biomolecular Chemistry: 10.1039/D1OB00608H
2020
Use of an asparaginyl endopeptidase for chemo-enzymatic peptide and protein labeling
T. M. Simon Tang, Davide Cardella, Alex J Lander, Xue Fei Li, Jorge S Escudero, Yu-Hsuan Tsai, Louis Y. P. Luk
Chemical Science: 10.1039/D0SC02023K
2018
'AND'-based fluorescence scaffold for the detection of ROS/RNS and a second analyte
Maria L. Odyniec, Adam C. Sedgwick, Alexander H. Swan, Maria Weber, Simon Tang, Jordan E. Gardiner, Miao Zhang, Yun Bao Jiang, Gabriele Kociok-Kohn, Robert B.P. Elmes, Steven D. Bull, Xiao Peng He, Tony D. James
Chemical Communications: 10.1039/c8cc04316g